How to deal with human spammers?
Using Jamroom
Yes - These are real people presumably paid to trawl the net and post spam. I get them regularly on my live sites as well. I don't think its much use blocking their IPs or email addresses as they just come back with different ones. I've recently put a notice on my signup page to the effect that spammers and their posts would be deleted immediately and it worked for a couple of days but someone chose to ignore it this morning. I might try the Strumelia tactic and set the site to 'Admin Approve' and add a couple of pertinent questions to the signup form to weed out non-relevent users.
Just delete the spammers' profiles. They, and all their posted content will be deleted.
hth