Change the icon size of the user images
Design and Skin Customization
I would turn it off. Its a development tool to help you locate something you can't find. Normally I would use that as the last thing to turn on when I really cant figure out where something is.
Other methods I use are:
#1) grab the class from the thing im looking for and do a search on that over the codebase, something like
class="block_content mt10"

#2) understand the structure of things, I know that screen is a profile screen, and I know that section is in the side bar, so I'd go look in the skin for a template called profile_header.tpl and see if it contained anything similar to profile_sidebar.tpl. Then go look down that code until I located the FOLLOWERS section and read the code to see where that lead me to. I'd eventually get to where I wanted to change.